Ieng Sary and Ieng Thirith, a husband-and-wife team of French-educated Communist revolutionaries who held senior positions in the Khmer Rouge government in Cambodia in the 1970s, were arrested in Phnom Penh on Monday and charged with crimes against humanity.

Mr. Ieng Sary, a onetime history and geography teacher who became the Khmer Rouge foreign minister and deputy prime minister, was also charged with war crimes.

The two were arrested at their Phnom Penh home, where they had lived for the past decade under a government amnesty granted to Mr. Ieng Sary in 1996. That amnesty may complicate his prosecution.