Deadly 1918 Epidemic Linked to Bird Flu, Scientists Say
The work, being published in the journals Nature and Science, involved getting the complete genetic sequence of the 1918 virus, using techniques of molecular biology to synthesize it, and then using it to infect mice and human lung cells in a specially equipped, secure lab at the Centers for Disease Control and Prevention in Atlanta.
The findings, the scientists say, reveal a small number of genetic changes that may explain why the virus was so lethal. The work also confirms the legitimacy of worries about the bird flu viruses that are now emerging in Asia.
The new studies find that today's bird flu viruses share some of the crucial genetic changes that occurred in the 1918 flu. The scientists suspect that with the 1918 flu, changes in just 25 to 30 out of about 4,400 amino acids in the viral proteins turned the virus into a killer. The bird flus, known as H5N1 viruses, have a few, but not all of those changes.
comments powered by Disqus
- Moving Photographs of Japanese American Internees, Then and Now
- A One-of-a-Kind Trove Reveals What 19th-Century American Boyhood Was Really Like
- St. Louis University moves controversial statue after protests
- UNC Renames Building That Honored Ku Klux Klan Leader
- A Wartime Bomb, Unearthed in Germany, Recalls Darker Days
- NYT hosts debate including Eric Foner: How Americans should remember Reconstruction
- William Leuchtenburg says historians and the media have been too hard on Obama
- Hugh Ambrose, historian who helped develop WWII Museum, dead at 48
- Historian discounts claim that Churchill and other British PM's were gay
- Nick Bunker Wins $50,000 2015 George Washington Book Prize