Deadly 1918 Epidemic Linked to Bird Flu, Scientists Say
The work, being published in the journals Nature and Science, involved getting the complete genetic sequence of the 1918 virus, using techniques of molecular biology to synthesize it, and then using it to infect mice and human lung cells in a specially equipped, secure lab at the Centers for Disease Control and Prevention in Atlanta.
The findings, the scientists say, reveal a small number of genetic changes that may explain why the virus was so lethal. The work also confirms the legitimacy of worries about the bird flu viruses that are now emerging in Asia.
The new studies find that today's bird flu viruses share some of the crucial genetic changes that occurred in the 1918 flu. The scientists suspect that with the 1918 flu, changes in just 25 to 30 out of about 4,400 amino acids in the viral proteins turned the virus into a killer. The bird flus, known as H5N1 viruses, have a few, but not all of those changes.
comments powered by Disqus
- Recalling a Film From the Liberation of the Camps
- Skull Fossil Offers New Clues on Human Journey From Africa
- Are crude conspiracies right? Research shows nations really do go to war over oil
- Famed SC civil rights protesters have convictions erased
- A Fight About Taxing The Wealthy, A Century Before President Obama
- Claire Strom to Step Down as Editor of Agricultural History
- Joan Peters’s legacy assessed by one of her fiercest critics, Norman Finkelstein
- West Point historian says if his cadets can understand the history of war, so can Congress
- Australian historian Alan Atkinson wins $100,000 literary prize
- From his perch in Saudi Arabia, Princeton’s Mark Cohen says Jews and Muslims should remember they used to get along